OXR1

Across TCGA cell cohorts, OXR1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OXR1-associated genes across cancer lineages are SEL1L2, SNU13, and VAX1. Each is linked with OXR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXR1-to-partner and partner-to-OXR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEL1L2 grouped by OXR1-low versus OXR1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXR1→partner) and Y-score (partner→OXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SEL1L2 →	+0.030	+5.087	<.001	.004	3	1
LARGE_INTESTINE	SNU13 →	+0.480	+2.628	.001	.002	3	1
LARGE_INTESTINE	VAX1 →	+0.633	+2.197	<.001	.004	3	1
LARGE_INTESTINE	PDE3B →	-0.802	-2.541	.006	.005	3	1
LARGE_INTESTINE	HHEX →	+1.324	+2.628	<.001	.002	3	1
LARGE_INTESTINE	NPY2R →	+0.002	+2.310	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

SEL1L2 by OXR1 expression — URINARY_TRACT

Explore this box plot interactively →