OXNAD1

Across TCGA patient cohorts, OXNAD1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXNAD1-associated genes across cancer lineages are MSH6, ATM, and 14-3-3_beta. Each is linked with OXNAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXNAD1-to-partner and partner-to-OXNAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH6 grouped by OXNAD1-low versus OXNAD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXNAD1→partner) and Y-score (partner→OXNAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH6 →	-0.364	-1.678	.004	.023	3	2
UCEC	ATM →	-0.584	-2.794	<.001	.002	3	2
UCEC	14-3-3_beta →	-0.106	-1.973	.005	.029	3	1
UCEC	eEF2 →	+0.406	+2.321	.003	.033	3	1
UCEC	A-Raf_pS299 →	-0.134	-2.087	.003	.005	3	1
UCEC	ERK2 →	+0.212	+2.584	.004	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

MSH6 by OXNAD1 expression — UCEC

Explore this box plot interactively →