OXNAD1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OXNAD1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OXNAD1-associated genes across cancer lineages are OR2A14, CLPSL1, and MYH8. Each is linked with OXNAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXNAD1-to-partner and partner-to-OXNAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2A14 grouped by OXNAD1-low versus OXNAD1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXNAD1→partner) and Y-score (partner→OXNAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaOR2A14 →+0.033+4.807<.001.00631
BLOOD_LeukemiaCLPSL1 →+0.040+5.201<.001.00631
LARGE_INTESTINEMYH8 →+0.089+2.657<.001.00731
LARGE_INTESTINEMYH13 →+0.387+2.791.004.00531
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR2A14 by OXNAD1 expression — BLOOD_Myeloma

Box plot of OR2A14 in OXNAD1-low vs OXNAD1-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration