Across TCGA pan-cancer cohorts, OXLD1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OXLD1 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OXLD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated OXLD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

HNSC, PDAC, and CCRCC are the cancer types where OXLD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.495	0.871	<.001	65	view →
PDAC	DFS	Quartile	II,III,IV	0.349	0.776	.008	15	view →
CCRCC	OS	Median	II,III,IV	1.000	0.499	.025	6	view →
LSCC	DFS	Quartile	All	0.319	0.830	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OXLD1 tumor-vs-normal RNA expression · all OXLD1 data types