OXGR1

Across TCGA patient cohorts, OXGR1 mutation is significantly associated with the RNA expression of many other genes, with 730 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXGR1-associated genes across cancer lineages are SAC3D1, RN7SL100P, and CPQ. Each is linked with OXGR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OXGR1-to-partner and partner-to-OXGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAC3D1 grouped by OXGR1-low versus OXGR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXGR1→partner) and Y-score (partner→OXGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAC3D1 →	+0.669	+3.606	<.001	.001	3	3
LUSC	RN7SL100P →	+0.214	+5.038	<.001	.009	3	2
UCEC	CPQ →	-0.673	-2.799	<.001	.003	3	2
UCEC	MAP2K2 →	+0.346	+2.609	.009	.006	3	2
UCEC	DOHH →	+0.600	+3.130	<.001	<.001	3	2
UCEC	TNFRSF11A →	-0.589	-3.435	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 730 associations by consensus.

SAC3D1 by OXGR1 expression — UCEC

Explore this box plot interactively →