OXGR1

Across TCGA cell cohorts, OXGR1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OXGR1-associated genes across cancer lineages are TRIM49, PRND, and TRIM49B. Each is linked with OXGR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXGR1-to-partner and partner-to-OXGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM49 grouped by OXGR1-low versus OXGR1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXGR1→partner) and Y-score (partner→OXGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	TRIM49 →	+0.019	+4.285	<.001	.003	3	1
BLOOD_Myeloma	PRND →	+0.049	+3.906	.003	.009	3	1
BLOOD_Myeloma	TRIM49B →	+0.368	+4.285	.003	.003	3	1
LIVER	GIMAP1 →	+0.007	+3.977	<.001	.006	3	1
KIDNEY	FGF4 →	+0.007	+4.491	<.001	.002	3	1
BLOOD_Lymphoma	IGSF5 →	+0.104	+2.874	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

TRIM49 by OXGR1 expression — BLOOD_Myeloma

Explore this box plot interactively →