Across TCGA patient cohorts, OXCT2 mutation is significantly associated with the RNA expression of many other genes, with 504 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXCT2-associated genes across cancer lineages are RNU6-752P, RNA5SP34, and SNRPCP20. Each is linked with OXCT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXCT2-to-partner and partner-to-OXCT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXCT2→partner) and Y-score (partner→OXCT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-752P →	+0.160	+3.990	<.001	.009	3	2
SKCM	RNA5SP34 →	+0.122	+5.003	<.001	.002	3	2
UCEC	SNRPCP20 →	+0.246	+2.633	<.001	.001	3	2
CESC	LINC02559 →	+1.025	+5.342	<.001	.002	3	2
UCEC	CDCA2 →	+0.882	+3.600	.002	.001	3	2
UCEC	TRIM53CP →	+0.395	+2.483	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 504 associations by consensus.

Exploration

OXCT2 survival (RNA) · tumor vs normal (RNA) · all OXCT2 data types