Across TCGA patient cohorts, OXCT2 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXCT2-associated genes across cancer lineages are ERK2, ATM, and Di-Ras3. Each is linked with OXCT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXCT2-to-partner and partner-to-OXCT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXCT2→partner) and Y-score (partner→OXCT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.233	+2.321	.016	.035	3	2
UCEC	ATM →	-0.615	-2.321	.006	.035	3	2
UCEC	Di-Ras3 →	-0.216	-2.321	.003	.035	3	2
UCEC	eIF4E →	+0.234	+3.459	.027	.005	3	1
UCEC	Ku80 →	+0.309	+3.472	.009	.002	3	1
UCEC	MEK1 →	+0.441	+3.459	.016	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

OXCT2 survival (RNA) · tumor vs normal (RNA) · all OXCT2 data types