Across TCGA cell cohorts, OXCT2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OXCT2-associated genes across cancer lineages are ACER1, RSC1A1, and KIR3DL2. Each is linked with OXCT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OXCT2-to-partner and partner-to-OXCT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXCT2→partner) and Y-score (partner→OXCT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.115	+3.716	<.001	.003	3	1
LARGE_INTESTINE	RSC1A1 →	+0.908	+3.782	.001	.002	3	1
LARGE_INTESTINE	KIR3DL2 →	+0.055	+4.141	<.001	<.001	3	1
LARGE_INTESTINE	GAS2L2 →	+0.103	+3.807	<.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

OXCT2 survival (RNA) · tumor vs normal (RNA) · all OXCT2 data types