OXCT1-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, OXCT1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of OXCT1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OXCT1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types OXCT1-AS1 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA, UCEC, and BRCA are the cancer types where OXCT1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OXCT1-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAMaleAll−0.841<.0019view →
UCECAllAll−1.063<.0016view →
BRCAAllAll−1.045<.0016view →
STADAllAll−0.340.0045view →
BLCAAllIV−0.947.0024view →
READAllAll−0.598.0013view →
LUADAllII,III,IV−0.182.0093view →
KIRCMaleII,III,IV−0.396.0142view →
ESCAAllII,III,IV−0.294.0232view →
PRADAllAll−0.268.0022view →
LUSCAllAll+0.204.0381view →
LIHCAllAll+0.057.0311view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

OXCT1-AS1–THCA

Tumor-vs-normal expression box plot for OXCT1-AS1 RNA in THCA.

Open the THCA breakdown →

Exploration