OXA1L

Across TCGA pan-cancer cohorts, OXA1L Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OXA1L data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher OXA1L Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OXA1L expression acts as an unfavorable survival marker.

LUSC, COAD, and LIHC are the cancer types where OXA1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.132	0.760	<.001	33	view →
COAD	DFS	Median	All	0.187	0.783	<.001	27	view →
LIHC	DFS	Median	All	0.044	0.553	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	IV	0.179	0.755	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OXA1L–LUSC (DFS)

Open the LUSC breakdown →