OXA1L

Across TCGA pan-cancer cohorts, OXA1L mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OXA1L data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher OXA1L mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated OXA1L expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where OXA1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	IV	0.220	0.781	.017	7	view →
LSCC	DFS	Tertile	II,III,IV	0.899	0.559	.025	4	view →
LUAD	OS	Quartile	III,IV	1.000	0.276	.040	2	view →
HNSC	DFS	Tertile	All	0.733	0.517	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OXA1L–CCRCC (DFS)

Open the CCRCC breakdown →