OXA1L

Across TCGA patient cohorts, OXA1L mutation is significantly associated with the RNA expression of many other genes, with 1,227 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OXA1L-associated genes across cancer lineages are PLEKHH3, TFAP2C, and RAB28P4. Each is linked with OXA1L in more than 1 cancer types. Because this analysis shows association rather than direction, both OXA1L-to-partner and partner-to-OXA1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLEKHH3 grouped by OXA1L-low versus OXA1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OXA1L→partner) and Y-score (partner→OXA1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLEKHH3 →	+0.600	+2.711	.002	.003	3	2
UCEC	TFAP2C →	-1.525	-3.542	<.001	.002	3	2
SKCM	RAB28P4 →	+0.032	+4.070	<.001	<.001	3	2
SKCM	MTND1P33 →	+0.014	+3.209	<.001	.004	3	2
UCEC	CIDECP1 →	+0.464	+3.601	<.001	.001	3	2
UCEC	RNA5SP391 →	+0.273	+4.777	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,227 associations by consensus.

PLEKHH3 by OXA1L expression — UCEC

Explore this box plot interactively →