OVOL3

Across TCGA patient cohorts, OVOL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OVOL3-associated proteins across cancer lineages are AKAP8L, SF3B2, and HCFC1. Each is linked with OVOL3 in more than 6 cancer types. Because this analysis shows association rather than direction, both OVOL3-to-partner and partner-to-OVOL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OVOL3 versus AKAP8L in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OVOL3→partner) and Y-score (partner→OVOL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AKAP8L →	+0.304	+0.554	<.001	<.001	3	7
GBM	SF3B2 →	+0.229	+0.410	.002	.001	3	6
HNSC	HCFC1 →	+0.190	+0.489	<.001	<.001	3	6
GBM	SNRPD2 →	+0.255	+0.485	.003	<.001	3	6
HNSC	ZNF326 →	+0.358	+0.667	<.001	<.001	3	6
GBM	SMC1A →	+0.335	+0.498	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,407 associations by consensus.

OVOL3 vs AKAP8L — GBM

Explore this scatter interactively →