OVOL2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OVOL2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OVOL2-associated genes across cancer lineages are OR4F5. Each is linked with OVOL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OVOL2-to-partner and partner-to-OVOL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F5 grouped by OVOL2-low versus OVOL2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVOL2→partner) and Y-score (partner→OVOL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR4F5 →+0.024+3.345<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR4F5 by OVOL2 expression — LARGE_INTESTINE

Box plot of OR4F5 in OVOL2-low vs OVOL2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration