OVGP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OVGP1 mutation is significantly associated with the RNA expression of many other genes, with 3,957 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OVGP1-associated genes across cancer lineages are STMN1P2, RNA5SP419, and RN7SL148P. Each is linked with OVGP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OVGP1-to-partner and partner-to-OVGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STMN1P2 grouped by OVGP1-low versus OVGP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVGP1→partner) and Y-score (partner→OVGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCASTMN1P2 →+0.115+4.433<.001.00733
UCECRNA5SP419 →+0.466+2.077.001.00133
HNSCRN7SL148P →+0.088+4.883<.001.00433
UCECMIR3651 →+0.429+1.911<.001.00132
BLCAEIF4EP5 →+0.063+4.653.002.00132
BLCARNU4-14P →+0.447+4.266<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,957 associations by consensus.

STMN1P2 by OVGP1 expression — BLCA

Box plot of STMN1P2 in OVGP1-low vs OVGP1-high samples in BLCA.

Explore this box plot interactively →

Exploration