OVGP1

Across TCGA cell cohorts, OVGP1 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OVGP1-associated genes across cancer lineages are CSN2, USP9Y, and VPS4B. Each is linked with OVGP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OVGP1-to-partner and partner-to-OVGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSN2 grouped by OVGP1-low versus OVGP1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVGP1→partner) and Y-score (partner→OVGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CSN2 →	+0.108	+4.392	.001	.003	3	1
LARGE_INTESTINE	USP9Y →	+1.871	+3.540	<.001	.002	3	1
LARGE_INTESTINE	VPS4B →	+0.834	+3.082	.001	.007	3	1
LARGE_INTESTINE	BBS7 →	+0.631	+3.064	.005	.009	3	1
LARGE_INTESTINE	ETNK1 →	+0.745	+3.137	<.001	.007	3	1
LARGE_INTESTINE	C18orf21 →	+0.596	+3.064	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

CSN2 by OVGP1 expression — OESOPHAGUS

Explore this box plot interactively →