OVGP1

Across TCGA cell cohorts, OVGP1 mutation is significantly associated with the mutation status of many other genes, with 3,872 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OVGP1-associated genes across cancer lineages are NLRP9, STARD13, and ITGA9. Each is linked with OVGP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OVGP1-to-partner and partner-to-OVGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NLRP9 grouped by OVGP1-low versus OVGP1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVGP1→partner) and Y-score (partner→OVGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	NLRP9 →	+3.087	+4.000	.008	.008	1	4
SOFT_TISSUE	STARD13 →	+5.502	+5.502	.003	.003	1	4
OVARY	ITGA9 →	+5.415	+5.415	.004	.004	1	4
SOFT_TISSUE	COL4A1 →	+5.502	+5.502	.003	.003	1	4
SOFT_TISSUE	TNRC6C →	+4.502	+5.066	.007	.007	1	4
LARGE_INTESTINE	RASGRF1 →	+2.632	+4.754	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,872 associations by consensus.

NLRP9 by OVGP1 expression — OESOPHAGUS

Explore this box plot interactively →