Across TCGA patient cohorts, OVCH1 mutation is significantly associated with the RNA expression of many other genes, with 6,378 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OVCH1-associated genes across cancer lineages are DLGAP5, B3GNT4, and CCL14. Each is linked with OVCH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OVCH1-to-partner and partner-to-OVCH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVCH1→partner) and Y-score (partner→OVCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DLGAP5 →	+0.746	+1.711	<.001	<.001	3	4
COAD	B3GNT4 →	+0.488	+3.584	<.001	.002	3	4
LUAD	CCL14 →	-0.399	-2.493	.006	.001	3	4
UCEC	DEPDC1 →	+0.614	+1.873	<.001	<.001	3	4
UCEC	GLB1L →	-0.450	-3.381	<.001	<.001	3	4
LGG	RN7SKP121 →	+0.124	+7.977	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,378 associations by consensus.

Exploration

OVCH1 survival (RNA) · tumor vs normal (RNA) · all OVCH1 data types