Across TCGA patient cohorts, OVCH1 mutation is significantly associated with the total protein of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OVCH1-associated genes across cancer lineages are PCNA, CD31, and eIF4E. Each is linked with OVCH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OVCH1-to-partner and partner-to-OVCH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVCH1→partner) and Y-score (partner→OVCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCNA →	+0.281	+3.330	.015	.005	3	4
LUSC	CD31 →	-0.222	-3.000	.001	.033	3	3
UCEC	eIF4E →	+0.185	+1.678	.001	<.001	3	3
UCEC	STAT3_pY705 →	-0.272	-1.253	<.001	.016	3	3
UCEC	4E-BP1 →	+0.324	+2.736	<.001	<.001	3	3
LUSC	14-3-3_beta →	-0.099	-2.575	.043	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

Exploration

OVCH1 survival (RNA) · tumor vs normal (RNA) · all OVCH1 data types