Across TCGA cell cohorts, OVCH1 mutation is significantly associated with the RNA expression of many other genes, with 260 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OVCH1-associated genes across cancer lineages are TAAR8, CALHM4, and C11orf91. Each is linked with OVCH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OVCH1-to-partner and partner-to-OVCH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVCH1→partner) and Y-score (partner→OVCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TAAR8 →	+0.023	+5.614	<.001	.002	3	2
LUNG_SCLC	CALHM4 →	+0.939	+3.479	.002	.007	3	2
LUNG_SCLC	C11orf91 →	+0.160	+3.887	.001	.001	3	2
BLOOD_Leukemia	KRTAP12-3 →	+0.124	+5.539	<.001	.003	3	2
LARGE_INTESTINE	UFSP2 →	+0.463	+3.082	.005	.007	3	2
LARGE_INTESTINE	ESYT1 →	+0.492	+2.628	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 260 associations by consensus.

Exploration

OVCH1 survival (RNA) · tumor vs normal (RNA) · all OVCH1 data types