OVCH1-AS1

Across TCGA pan-cancer cohorts, OVCH1-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of OVCH1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OVCH1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types OVCH1-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and LUSC are the cancer types where OVCH1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OVCH1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.382	<.001	7	view →
BRCA	All	III,IV	−0.255	<.001	6	view →
LUSC	All	All	−0.276	.001	5	view →
KICH	All	II,III,IV	−0.306	.004	3	view →
KIRP	Female	All	−0.142	.011	3	view →
KIRC	All	All	+0.175	.011	2	view →
BLCA	Male	All	−0.144	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

OVCH1-AS1–THCA

Open the THCA breakdown →