OTULINL

Across TCGA pan-cancer cohorts, OTULINL mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OTULINL data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OTULINL mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated OTULINL expression acts as an unfavorable survival marker.

UCEC, CCRCC, and HNSC are the cancer types where OTULINL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.809	0.978	.003	12	view →
CCRCC	OS	Median	IV	0.194	0.647	.049	2	view →
HNSC	DFS	Median	II,III,IV	0.912	0.992	.029	1	view →
LUAD	DFS	Quartile	II,III,IV	0.617	0.889	.028	1	view →
LSCC	OS	Quartile	II,III,IV	0.734	1.000	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OTULINL–UCEC (DFS)

Open the UCEC breakdown →