OTULINL

Across TCGA cell cohorts, OTULINL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,165 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OTULINL-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with OTULINL in more than 6 cancer types. Because this analysis shows association rather than direction, both OTULINL-to-partner and partner-to-OTULINL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by OTULINL-low versus OTULINL-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTULINL→partner) and Y-score (partner→OTULINL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.125	+1.074	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.108	+1.061	.002	.004	3	7
OVARY	Negative regulation of myoblast fusion →	+0.111	+1.568	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+1.146	.001	<.001	3	7
LUNG_SCLC	Cellular response to rapamycin →	+0.123	+2.163	.001	<.001	3	7
LARGE_INTESTINE	Positive regulation of Arp2/3 complex-mediated actin nucleation →	-0.108	-1.842	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,165 associations by consensus.

Establishment of mitotic sister chromatid cohesion by OTULINL expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →