OTUD7B

Across TCGA patient cohorts, OTUD7B protein abundance is significantly associated with the RNA expression of many other genes, with 12,927 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OTUD7B-associated genes across cancer lineages are LYSMD1, CEP350, and ENSA. Each is linked with OTUD7B in more than 7 cancer types. Because this analysis shows association rather than direction, both OTUD7B-to-partner and partner-to-OTUD7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTUD7B versus LYSMD1 in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD7B→partner) and Y-score (partner→OTUD7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LYSMD1 →	+0.860	+0.374	<.001	<.001	3	8
UCEC	CEP350 →	+0.596	+0.264	<.001	<.001	3	7
LUAD	ENSA →	+0.509	+0.181	<.001	<.001	3	7
BRCA	SDE2 →	+0.550	+0.300	<.001	<.001	3	7
BRCA	CNST →	+0.582	+0.343	<.001	<.001	3	7
LUAD	RNF115 →	+0.432	+0.214	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,927 associations by consensus.

OTUD7B vs LYSMD1 — HNSC

Explore this scatter interactively →