OTUD7B

Across TCGA cell cohorts, OTUD7B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,387 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OTUD7B-associated GO terms across cancer lineages are Positive regulation of TORC2 signaling, Cytosolic transport, and Retrograde transport, endosome to Golgi. Each is linked with OTUD7B in more than 17 cancer types. Because this analysis shows association rather than direction, both OTUD7B-to-partner and partner-to-OTUD7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of TORC2 signaling grouped by OTUD7B-low versus OTUD7B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD7B→partner) and Y-score (partner→OTUD7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of TORC2 signaling →	+0.138	+0.822	.002	.001	3	18
STOMACH	Cytosolic transport →	+0.073	+1.068	.004	<.001	3	17
STOMACH	Retrograde transport, endosome to Golgi →	+0.077	+0.893	.003	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.076	+1.079	<.001	<.001	3	16
STOMACH	Macroautophagy →	+0.092	+1.054	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.085	+1.042	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,387 associations by consensus.

Positive regulation of TORC2 signaling by OTUD7B expression — STOMACH

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