OTUD7A

Across TCGA cell cohorts, OTUD7A mutation is significantly associated with the RNA expression of many other genes, with 139 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OTUD7A-associated genes across cancer lineages are KRT28, PRAMEF20, and DPRX. Each is linked with OTUD7A in more than 1 cancer types. Because this analysis shows association rather than direction, both OTUD7A-to-partner and partner-to-OTUD7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT28 grouped by OTUD7A-low versus OTUD7A-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD7A→partner) and Y-score (partner→OTUD7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	KRT28 →	+0.016	+4.906	<.001	.006	3	2
CNS	PRAMEF20 →	+0.569	+5.044	<.001	.001	3	2
CNS	DPRX →	+0.050	+4.321	<.001	.009	3	2
OESOPHAGUS	FAM71B →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	LCE1D →	+0.206	+4.906	<.001	.006	3	1
OESOPHAGUS	OR13C2 →	+0.033	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

KRT28 by OTUD7A expression — OESOPHAGUS

Explore this box plot interactively →