OTUD5

Across TCGA cell cohorts, OTUD5 mutation is significantly associated with the drug of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OTUD5-associated genes across cancer lineages are Cytarabine, Vismodegib, and Staurosporine. Each is linked with OTUD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OTUD5-to-partner and partner-to-OTUD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytarabine grouped by OTUD5-low versus OTUD5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD5→partner) and Y-score (partner→OTUD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cytarabine →	+1.101	+2.655	.003	.044	3	1
LARGE_INTESTINE	Vismodegib →	+0.294	+2.807	.037	.046	3	1
LARGE_INTESTINE	Staurosporine →	+0.491	+2.868	.027	.022	3	1
LARGE_INTESTINE	Bleomycin (10 uM) →	+0.696	+2.649	.027	.046	3	1
LARGE_INTESTINE	CZC24832 →	+0.259	+2.868	.035	.022	3	1
LARGE_INTESTINE	GSK2276186C →	+0.510	+2.900	.019	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Cytarabine by OTUD5 expression — LARGE_INTESTINE

Explore this box plot interactively →