OTUD1

Across TCGA patient cohorts, OTUD1 mutation is significantly associated with the RNA expression of many other genes, with 1,881 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OTUD1-associated genes across cancer lineages are LINC01072, TRIM53CP, and TRIM48. Each is linked with OTUD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OTUD1-to-partner and partner-to-OTUD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by OTUD1-low versus OTUD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD1→partner) and Y-score (partner→OTUD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01072 →	+0.130	+2.225	<.001	.008	3	2
UCEC	TRIM53CP →	+0.392	+2.150	.002	.002	3	2
COAD	TRIM48 →	+0.079	+4.070	.002	.009	3	2
UCEC	YTHDF3-AS1 →	+0.672	+3.483	<.001	.002	3	1
UCEC	IGKV1OR2-118 →	+0.180	+2.326	.007	.001	3	1
UCEC	BNIP3P4 →	+0.071	+2.784	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,881 associations by consensus.

LINC01072 by OTUD1 expression — UCEC

Explore this box plot interactively →