OTUD1

Across TCGA cell cohorts, OTUD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,103 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OTUD1-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Regulation of apoptotic signaling pathway. Each is linked with OTUD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both OTUD1-to-partner and partner-to-OTUD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by OTUD1-low versus OTUD1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD1→partner) and Y-score (partner→OTUD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Process utilizing autophagic mechanism →	+0.045	+1.369	<.001	.004	3	9
BLOOD_Lymphoma	Autophagy →	+0.045	+1.369	<.001	.004	3	9
BREAST	Regulation of apoptotic signaling pathway →	+0.072	+1.187	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of protein binding →	+0.079	+0.777	.001	<.001	3	9
STOMACH	Response to unfolded protein →	+0.073	+1.246	.001	.003	2	9
PANCREAS	Hormone-mediated signaling pathway →	+0.058	+1.292	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,103 associations by consensus.

Process utilizing autophagic mechanism by OTUD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →