OTUB2

Across TCGA cell cohorts, OTUB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,651 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OTUB2-associated GO terms across cancer lineages are Purine ribonucleoside monophosphate metabolic process, Striated muscle contraction, and SNARE complex disassembly. Each is linked with OTUB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both OTUB2-to-partner and partner-to-OTUB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleoside monophosphate metabolic process grouped by OTUB2-low versus OTUB2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUB2→partner) and Y-score (partner→OTUB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Purine ribonucleoside monophosphate metabolic process →	+0.079	+0.544	<.001	<.001	3	8
SOFT_TISSUE	Striated muscle contraction →	+0.062	+0.541	.001	<.001	3	8
OESOPHAGUS	SNARE complex disassembly →	+0.149	+0.896	<.001	.003	3	7
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.146	+0.466	<.001	<.001	3	7
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.146	+0.466	<.001	<.001	3	7
URINARY_TRACT	Regulation of cardiac muscle tissue development →	-1.258	-0.708	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,651 associations by consensus.

Purine ribonucleoside monophosphate metabolic process by OTUB2 expression — BLOOD_Leukemia

Explore this box plot interactively →