OTUB1

Across TCGA patient cohorts, OTUB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,098 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OTUB1-associated proteins across cancer lineages are STIP1, NAA40, and ZNHIT2. Each is linked with OTUB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both OTUB1-to-partner and partner-to-OTUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTUB1 versus STIP1 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUB1→partner) and Y-score (partner→OTUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STIP1 →	+0.205	+0.396	<.001	<.001	3	6
OV	NAA40 →	+0.529	+0.453	<.001	<.001	3	5
OV	ZNHIT2 →	+0.231	+0.237	.001	.002	3	4
HNSC	TXNDC5 →	-0.621	-0.303	<.001	.009	3	4
LSCC	FEN1 →	+0.523	+0.369	<.001	<.001	3	4
LSCC	AASDHPPT →	+0.241	+0.265	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,098 associations by consensus.

OTUB1 vs STIP1 — HNSC

Explore this scatter interactively →