OTP

Across TCGA patient cohorts, OTP protein abundance is significantly associated with the RNA expression of many other genes, with 179 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OTP-associated genes across cancer lineages are RANBP9, TSC22D1, and MEGF9. Each is linked with OTP in more than 1 cancer types. Because this analysis shows association rather than direction, both OTP-to-partner and partner-to-OTP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTP versus RANBP9 in GBM, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTP→partner) and Y-score (partner→OTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RANBP9 →	+0.557	+0.703	.003	.002	3	1
GBM	TSC22D1 →	+1.323	+0.703	.009	.002	3	1
GBM	MEGF9 →	+0.683	+0.703	.007	.002	3	1
GBM	AK1 →	+1.993	+0.959	.003	.008	3	1
GBM	NDUFS8 →	+0.584	+0.703	.006	.002	3	1
GBM	CMAS →	+0.399	+0.704	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 179 associations by consensus.

OTP vs RANBP9 — GBM

Explore this scatter interactively →