Across TCGA patient cohorts, OTOP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,386 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OTOP2-associated proteins across cancer lineages are LGALSL, P2RY1_S346, and TNS3_S1149. Each is linked with OTOP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OTOP2-to-partner and partner-to-OTOP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OTOP2→partner) and Y-score (partner→OTOP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LGALSL →	+0.613	+0.510	<.001	.005	3	3
LSCC	P2RY1_S346 →	+0.801	+0.725	<.001	<.001	3	3
HNSC	TNS3_S1149 →	-0.504	-0.575	.004	.005	3	3
LSCC	BAIAP2 →	+0.528	+0.459	<.001	<.001	3	3
HNSC	BAIAP2_S454 →	+0.969	+0.590	<.001	<.001	3	3
LSCC	PLCD1 →	+0.465	+0.539	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,386 associations by consensus.

Exploration

OTOP2 survival (RNA) · tumor vs normal (RNA) · all OTOP2 data types