Across TCGA cell cohorts, OTOP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 292 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OTOP2-associated GO terms across cancer lineages are Regulation of arachidonate secretion, Response to glucocorticoid, and Positive regulation of sodium ion transmembrane transport. Each is linked with OTOP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OTOP2-to-partner and partner-to-OTOP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTOP2→partner) and Y-score (partner→OTOP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of arachidonate secretion →	-0.182	-0.207	<.001	.005	3	3
UPPER_AERODIGESTIVE_TRACT	Response to glucocorticoid →	+0.083	+0.332	<.001	.004	2	4
SOFT_TISSUE	Positive regulation of sodium ion transmembrane transport →	-0.168	-0.014	.009	.007	3	3
SOFT_TISSUE	Lipoxin A4 metabolic process →	-0.706	-0.010	.002	.002	3	3
SOFT_TISSUE	Pericardium development →	+0.899	+0.010	.001	.007	3	3
SOFT_TISSUE	Determination of adult lifespan →	+0.084	+0.011	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

Exploration

OTOP2 survival (RNA) · tumor vs normal (RNA) · all OTOP2 data types