OTOGL

Across TCGA patient cohorts, OTOGL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,455 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OTOGL-associated proteins across cancer lineages are TMOD2, PURA, and CAP2. Each is linked with OTOGL in more than 3 cancer types. Because this analysis shows association rather than direction, both OTOGL-to-partner and partner-to-OTOGL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTOGL versus TMOD2 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OTOGL→partner) and Y-score (partner→OTOGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMOD2 →	+0.521	+0.460	<.001	.003	3	4
GBM	PURA →	+0.413	+0.634	<.001	<.001	3	4
HNSC	CAP2 →	+0.843	+0.404	<.001	.001	3	4
CCRCC	DDAH1 →	+0.676	+0.986	<.001	<.001	3	4
GBM	TLR2 →	-0.482	-0.481	.002	<.001	3	3
GBM	CALR →	-0.411	-0.710	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,455 associations by consensus.

OTOGL vs TMOD2 — UCEC

Explore this scatter interactively →