OTOGL

Across TCGA cell cohorts, OTOGL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,851 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OTOGL-associated GO terms across cancer lineages are Vacuole organization, Autophagosome assembly, and Macroautophagy. Each is linked with OTOGL in more than 6 cancer types. Because this analysis shows association rather than direction, both OTOGL-to-partner and partner-to-OTOGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by OTOGL-low versus OTOGL-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTOGL→partner) and Y-score (partner→OTOGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Vacuole organization →	+0.047	+0.331	<.001	.002	3	7
BREAST	Autophagosome assembly →	+0.035	+0.306	.005	.008	3	7
BREAST	Macroautophagy →	+0.057	+0.414	<.001	.004	3	6
BLOOD_Lymphoma	Autophagosome organization →	+0.047	+0.417	<.001	.008	3	6
BLOOD_Lymphoma	Cellular response to type I interferon →	+0.146	+0.763	<.001	<.001	3	6
BREAST	Process utilizing autophagic mechanism →	+0.039	+0.302	.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,851 associations by consensus.

Vacuole organization by OTOGL expression — BREAST

Explore this box plot interactively →