OSTM1

Across TCGA pan-cancer cohorts, OSTM1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OSTM1 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher OSTM1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated OSTM1 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and HNSC are the cancer types where OSTM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.339	1.000	.003	45	view →
PDAC	DFS	Tertile	All	0.270	0.460	.001	40	view →
HNSC	OS	Median	IV	0.647	0.843	.034	1	view →
LUAD	OS	Median	All	0.921	0.999	.011	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OSTM1–CCRCC (OS)

Open the CCRCC breakdown →