Across TCGA patient cohorts, OSTC protein abundance is significantly associated with the RNA expression of many other genes, with 6,351 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OSTC-associated genes across cancer lineages are DPP4, DPP4-DT, and FHL5. Each is linked with OSTC in more than 6 cancer types. Because this analysis shows association rather than direction, both OSTC-to-partner and partner-to-OSTC results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSTC→partner) and Y-score (partner→OSTC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DPP4 →	-1.972	-1.314	<.001	<.001	3	7
LUAD	DPP4-DT →	-1.548	-1.335	<.001	<.001	3	5
BRCA	FHL5 →	-0.884	-0.556	<.001	<.001	3	5
UCEC	CPA3 →	-1.170	-0.851	<.001	.001	3	4
LSCC	LRRK2 →	-1.326	-0.477	<.001	.001	3	4
BRCA	TPSB2 →	-1.260	-0.426	.002	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,351 associations by consensus.

Exploration

OSTC survival (RNA) · tumor vs normal (RNA) · all OSTC data types