Across TCGA cell cohorts, OST4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,206 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OST4-associated GO terms across cancer lineages are Leading strand elongation, Mitochondrial tRNA wobble uridine modification, and Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with OST4 in more than 10 cancer types. Because this analysis shows association rather than direction, both OST4-to-partner and partner-to-OST4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OST4→partner) and Y-score (partner→OST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Leading strand elongation →	-0.170	-0.834	.001	<.001	3	11
BONE	Mitochondrial tRNA wobble uridine modification →	-0.190	-1.137	<.001	<.001	3	10
BONE	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.124	-0.657	.001	.001	3	10
SOFT_TISSUE	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	-0.124	-0.660	<.001	<.001	3	10
BONE	Positive regulation of DNA-directed DNA polymerase activity →	-0.215	-0.879	<.001	<.001	3	10
BONE	Protein localization to chromatin →	-0.117	-0.742	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,206 associations by consensus.

Exploration

OST4 survival (RNA) · tumor vs normal (RNA) · all OST4 data types