OSR2

Across TCGA cell cohorts, OSR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,834 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OSR2-associated GO terms across cancer lineages are Middle ear morphogenesis, Embryonic skeletal limb joint morphogenesis, and Limb joint morphogenesis. Each is linked with OSR2 in more than 15 cancer types. Because this analysis shows association rather than direction, both OSR2-to-partner and partner-to-OSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Middle ear morphogenesis grouped by OSR2-low versus OSR2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSR2→partner) and Y-score (partner→OSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Middle ear morphogenesis →	+1.717	+2.827	<.001	<.001	3	16
BLOOD_Leukemia	Embryonic skeletal limb joint morphogenesis →	-0.254	-1.585	<.001	<.001	3	12
BLOOD_Myeloma	Limb joint morphogenesis →	-0.321	-1.803	<.001	<.001	3	9
URINARY_TRACT	Osteoblast proliferation →	+0.185	+2.197	.003	<.001	2	9
BONE	Bone morphogenesis →	+0.096	+1.586	.004	.001	3	8
STOMACH	Positive regulation of gene expression, epigenetic →	+0.059	+1.388	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,834 associations by consensus.

Middle ear morphogenesis by OSR2 expression — URINARY_TRACT

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