OSGIN2

Across TCGA patient cohorts, OSGIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,424 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible OSGIN2-associated proteins across cancer lineages are VCPIP1, YTHDF3, and RIPK2_S363. Each is linked with OSGIN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OSGIN2-to-partner and partner-to-OSGIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSGIN2 versus VCPIP1 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSGIN2→partner) and Y-score (partner→OSGIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCPIP1 →	+0.259	+0.606	<.001	.001	3	4
OV	YTHDF3 →	+0.292	+0.709	.001	<.001	3	4
OV	RIPK2_S363 →	+0.622	+0.484	<.001	<.001	3	4
PDAC	RIPK2_S393 →	+0.600	+0.320	.001	.004	3	4
OV	STK3 →	+0.395	+0.632	<.001	<.001	3	4
HNSC	SRP54 →	-0.221	-0.594	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,424 associations by consensus.

OSGIN2 vs VCPIP1 — OV

Explore this scatter interactively →