OSGIN1

Across TCGA cell cohorts, OSGIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,375 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OSGIN1-associated GO terms across cancer lineages are Response to L-phenylalanine derivative, Response to thyroxine, and Cellular response to thyroid hormone stimulus. Each is linked with OSGIN1 in more than 13 cancer types. Because this analysis shows association rather than direction, both OSGIN1-to-partner and partner-to-OSGIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to L-phenylalanine derivative grouped by OSGIN1-low versus OSGIN1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSGIN1→partner) and Y-score (partner→OSGIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Response to L-phenylalanine derivative →	+0.167	+1.828	.004	.001	3	14
OESOPHAGUS	Response to thyroxine →	+0.253	+1.952	.002	<.001	3	13
LIVER	Cellular response to thyroid hormone stimulus →	+0.228	+2.901	.001	.004	2	13
KIDNEY	Lysosomal lumen pH elevation →	+0.185	+2.032	.001	<.001	3	12
LUNG_NSCLC_LUSC	Cellular response to jasmonic acid stimulus →	+1.711	+2.652	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Response to jasmonic acid →	+1.711	+2.652	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,375 associations by consensus.

Response to L-phenylalanine derivative by OSGIN1 expression — LUNG_SCLC

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