OSGEPL1

Across TCGA patient cohorts, OSGEPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSGEPL1-associated genes across cancer lineages are GTF3C3, ANKRD46, and KLHL23. Each is linked with OSGEPL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both OSGEPL1-to-partner and partner-to-OSGEPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSGEPL1 versus GTF3C3 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSGEPL1→partner) and Y-score (partner→OSGEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTF3C3 →	+0.485	+0.323	<.001	<.001	3	5
LSCC	ANKRD46 →	+0.661	+0.552	<.001	<.001	3	4
LSCC	KLHL23 →	+0.847	+0.408	<.001	<.001	3	4
UCEC	FAM96AP2 →	+1.037	+0.398	.002	.001	3	4
HNSC	WDR75 →	+0.666	+0.438	.002	<.001	3	4
HNSC	METTL21A →	+0.501	+0.436	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,704 associations by consensus.

OSGEPL1 vs GTF3C3 — HNSC

Explore this scatter interactively →