OSGEP

Across TCGA cell cohorts, OSGEP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,310 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OSGEP-associated GO terms across cancer lineages are DNA recombination, Endothelial to hematopoietic transition, and Double-strand break repair. Each is linked with OSGEP in more than 14 cancer types. Because this analysis shows association rather than direction, both OSGEP-to-partner and partner-to-OSGEP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA recombination grouped by OSGEP-low versus OSGEP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSGEP→partner) and Y-score (partner→OSGEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.088	+1.340	<.001	<.001	3	15
BONE	Endothelial to hematopoietic transition →	+0.110	+1.085	.001	<.001	3	14
URINARY_TRACT	Double-strand break repair →	+0.062	+1.028	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Telomere organization →	+0.089	+1.303	<.001	<.001	3	13
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.096	+0.748	.008	<.001	3	13
BONE	Replication fork processing →	+0.128	+0.761	.006	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,310 associations by consensus.

DNA recombination by OSGEP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →