OSCAR

Across TCGA pan-cancer cohorts, OSCAR Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated OSCAR data layer compared with 21 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OSCAR Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OSCAR expression acts as an unfavorable survival marker.

KIRC, LUSC, and OV are the cancer types where OSCAR Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.067	0.874	<.001	36	view →
LUSC	DFS	Median	II,III,IV	0.135	0.663	.015	12	view →
OV	DFS	Median	All	0.132	0.541	.001	6	view →
LIHC	OS	Median	All	0.025	0.775	<.001	6	view →
PRAD	DFS	Median	All	0.113	0.935	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUAD	OS	Median	All	0.407	0.790	.006	6	view →
SKCM	OS	Median	All	0.102	0.323	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

OSCAR–KIRC (OS)

Open the KIRC breakdown →