OSCAR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OSCAR RNA expression is significantly associated with the protein abundance of many other proteins, with 20,849 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSCAR-associated proteins across cancer lineages are MYO1F, NCF2, and PARVG. Each is linked with OSCAR in more than 9 cancer types. Because this analysis shows association rather than direction, both OSCAR-to-partner and partner-to-OSCAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSCAR versus MYO1F in GBM, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSCAR→partner) and Y-score (partner→OSCAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYO1F →+0.655+0.862<.001<.001310
GBMNCF2 →+0.796+0.805<.001<.001310
GBMPARVG →+0.688+0.903<.001<.001310
GBMAIF1 →+0.767+0.885<.001<.001310
GBMFERMT3 →+0.615+0.934<.001<.001310
GBMALOX5 →+0.791+0.890<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,849 associations by consensus.

OSCAR vs MYO1F — GBM

Per-sample scatter of OSCAR vs MYO1F in GBM (Pearson r = 0.68).

Explore this scatter interactively →

Exploration