OSCAR

Across TCGA patient cohorts, OSCAR protein abundance is significantly associated with the RNA expression of many other genes, with 5,021 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSCAR-associated genes across cancer lineages are CD300A, LRPPRC, and MEFV. Each is linked with OSCAR in more than 3 cancer types. Because this analysis shows association rather than direction, both OSCAR-to-partner and partner-to-OSCAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSCAR versus CD300A in GBM, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSCAR→partner) and Y-score (partner→OSCAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD300A →	+1.414	+1.024	.001	.002	3	4
GBM	LRPPRC →	-0.631	-1.066	<.001	.002	3	3
GBM	MEFV →	+1.521	+1.321	.001	<.001	3	3
GBM	FAM20A →	+0.923	+0.833	<.001	<.001	3	3
GBM	HLX →	+0.598	+0.897	<.001	.002	3	3
BRCA	TMEM255B →	+0.871	+0.732	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,021 associations by consensus.

OSCAR vs CD300A — GBM

Explore this scatter interactively →