OSBPL3

Across TCGA patient cohorts, OSBPL3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,837 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OSBPL3-associated genes across cancer lineages are GKAP1, SNRPCP19, and MYEF2. Each is linked with OSBPL3 in more than 6 cancer types. Because this analysis shows association rather than direction, both OSBPL3-to-partner and partner-to-OSBPL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL3 versus GKAP1 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL3→partner) and Y-score (partner→OSBPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GKAP1 →	-0.810	-0.305	<.001	.001	3	7
GBM	SNRPCP19 →	+0.843	+0.521	<.001	<.001	3	7
COAD	MYEF2 →	-1.160	-0.277	<.001	<.001	3	6
BRCA	ANXA2 →	+0.833	+0.384	<.001	<.001	3	6
GBM	BCOR →	-0.633	-0.404	<.001	<.001	3	6
BRCA	RAMP2-AS1 →	-0.992	-0.325	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,837 associations by consensus.

OSBPL3 vs GKAP1 — LSCC

Explore this scatter interactively →