OSBPL2

Across TCGA cell cohorts, OSBPL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,948 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OSBPL2-associated GO terms across cancer lineages are Regulation by virus of viral protein levels in host cell, Autophagy, and Process utilizing autophagic mechanism. Each is linked with OSBPL2 in more than 15 cancer types. Because this analysis shows association rather than direction, both OSBPL2-to-partner and partner-to-OSBPL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation by virus of viral protein levels in host cell grouped by OSBPL2-low versus OSBPL2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL2→partner) and Y-score (partner→OSBPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation by virus of viral protein levels in host cell →	+0.213	+1.087	<.001	<.001	3	16
OVARY	Autophagy →	+0.066	+0.887	<.001	<.001	3	16
OVARY	Process utilizing autophagic mechanism →	+0.066	+0.887	<.001	<.001	3	16
BONE	Post-Golgi vesicle-mediated transport →	+0.092	+0.754	<.001	<.001	3	16
KIDNEY	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.162	+1.033	.002	<.001	3	15
BONE	Endoplasmic reticulum unfolded protein response →	+0.099	+0.628	.007	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

Regulation by virus of viral protein levels in host cell by OSBPL2 expression — KIDNEY

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